1. According to Sackett et al*, evidence-based practice is the "integration of best research evidence with clinical expertise and patient values. (Sackett et al. 2000. Evidence based medicine. How to practice and teach EBM. Second edition. Churchill Livingstone. London.)
2. "Evidence-based medicine is the use of mathematical estimates of the risk of benefit and harm, derived from high-quality research on population samples, to inform clinical decision-making in the diagnosis, investigation or management of individual patients." Trisha Greenhalgh (extract from 'How to read a paper")
The Five Steps of Evidence-Based Medicine
(Adapted from: Sackett DL, Straus SE, Richardson WS [and others]. Evidence-Based Medicine: How to Practice and Teach EBM. 2d ed. London: Churchill-Livingstone, 2000:3-4.)
Translate information into answerable questions (e.g. PICO). (See Formulating Questions.)
Find the best evidence with which to answerthese questions. (See Finding the evidence/Types of evidence, then EB sources.)
Critically appraise the evidence validity and usefulness. (See Finding the Evidence/Levels of Evidence, then Critical Appraisal.)
Apply the results to your practice.
Evaluate your performance.
Interview with Sir Muir Gray on clinical pathways (and Map of Medicine)
